Cystatin E/CST6 Monoclonal Antibody
Produktgrößen
100 ul
£346,00
AN200026P-100UL
Über dieses Produkt
- SKU:
- AN200026P
- Zusätzliche Namen:
- CST 6;Cystatin 6;Cystatin E;Cystatin E/M;Cystatin M;Cystatin M/E;Cystatin6;Cystatin-6;CystatinE;Cystatin-E;CystatinM;Cystatin-M;Cysteine proteinase inhibitor;CYTM;CST6
- Anwendung:
- IHC-Paraffin
- Buffer:
- 0.2 um filtered solution in PBS
- translate.label.attr.clone:
- A870
- Klonalität:
- Monoclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- Cystatin E/M, also referred to as CST6, is a member of type 2 cysteine proteinase inhibitors of the cystatin superfamily, and inhibits papain and cathepsin B. Cystatin E is a low molecular mass secreted protein existing in both a glycosylated (17 kDa) and an unglycosylated (14 kDa) form, with two characteristic intrachain disulfide bridges. Expression of cystatin M/E is found to be restricted to the epidermis, more specifically in the stratum granulosum, sweat glands, sebaceous glands, and the hair follicles. In addition to its function as a cysteine protease inhibitor, cystatin M/E also serves as a target for cross-linking by transglutaminases. Accordingly, cystatin M/E was suggested to be involved in barrier formation and maintenance. Furthermore, studies have revealed that cystatin M/E is frequently epigenetically inactivated during breast carcinogenesis, and thus be regarded as a candidate of tumour suppressor gene.
- Host:
- Mouse
- Immunogen:
- Recombinant Human Cystatin E / CST6 protein
- Isotyp:
- IgG1
- Aufreinigung:
- Protein A Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Monoclonal Antibody
- Datenblatt des Herstellers:cst6_monoclonal_antibody-an200026p