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Antikörper

IL-1 beta/IL1B Monoclonal Antibody

Produktgrößen
20 ul
£167,00
AN200015P-20UL
100 ul
£346,00
AN200015P-100UL
Über dieses Produkt
SKU:
AN200015P
Zusätzliche Namen:
IL1F,IL-1F,pro IL1F,IL-1,IL1-BETA,IL1F2,IL1 beta,IL1B,catabolin,IL-1B,pro Catabolin,pro IL1B,pro IL1F2,pro leukocytic endogenous mediator,pro leukocytic pyrogen,pro lymphocyte activating factor,pro mononuclear cell factor,IL-1F2,IL 1B,IL-1 beta
Anwendung:
IHC-Paraffin
Buffer:
PBS
translate.label.attr.clone:
A859
Klonalität:
Monoclonal
Konzentration:
1 mg/ml
Weitere Details:
Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells. Plays a role in angiogenesis by inducing VEGF production synergistically with TNF and IL6. Involved in transduction of inflammation downstream of pyroptosis: its mature form is specifically released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore.
Host:
Mouse
Immunogen:
Recombinant Human IL-1 beta / IL1B Protein
Isotyp:
IgG1
Aufreinigung:
Protein A Purified
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C/-70[o]C Avoid freeze/thaw cycles., 2-8[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Monoclonal Antibody