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Antikörper

PE Anti-Human CD204 Antibody[7C9C20]

Produktgrößen
20 tests
£145,00
AN00876D-20TESTS
100 tests
£266,00
AN00876D-100TESTS
2 x 100 tests
£439,00
AN00876D-2X100TESTS
Über dieses Produkt
SKU:
AN00876D
Zusätzliche Namen:
Macrophage scavenger receptor,MSR,MSR1,SRA,CD204
Anwendung:
Flow Cytometry
Buffer:
PBS
translate.label.attr.clone:
7C9C20
Klonalität:
Monoclonal
Konjugat:
R-PE
Weitere Details:
CD204, also known as scavenger receptor A (SR-A) and the macrophage scavenger receptor (MSR), is one of the phagocytic pattern-recognition receptors (PRRs) expressed on macrophages and dendritic cells. CD204 was initially identified as a receptor mediating recognition and internalization of low-density lipoprotein (LDL) by macrophages and playing critical roles in atherogenesis. CD204 recognizes apoptotic cells, modified lipid proteins, and exogenous pathogen-associated molecular patterns (PAMPs), which results in the induction of innate immune and inflammatory responses. CD204 can act as a co-receptor for Toll-like receptors, such as TLR3, TLR4, or TLR9, to facilitate the expression of proinflammatory cytokines. CD204 has been implicated in several pathological processes such as Alzheimer's disease, sepsis, ischemic injury, and coronary artery disease.
Host:
Mouse
Immunogen:
CD204
Isotyp:
IgG2a, kappa
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
2-8[o]C Do not freeze. Protect from light.
Hersteller:
Elabscience
Typ:
Antibody: Monoclonal Antibody