Purified Anti-Mouse CD279 Antibody[RMP1-14], Functional Grade
Produktgrößen
100 ug
£89,00
AN007850-100UG
1 mg
£171,00
AN007850-1MG
5 mg
£490,00
AN007850-5MG
25 mg
£1515,00
AN007850-25MG
50 mg
£2247,00
AN007850-50MG
100 mg
£3211,00
AN007850-100MG
Über dieses Produkt
- SKU:
- AN007850
- Zusätzliche Namen:
- CD279 antigen,hPD 1,hPD l,Ly101,PD 1,Pdc1,PDCD 1,Programmed cell death 1 protein,Protein PD 1,Protein PD-1,Systemic lupus erythematosus susceptibility 2,hPD,mPD,Programmed Death,Programmed cell death,Programmed cell death protein,PDCD,hSLE,SLEB,PD-1,CD279,hPD-1,hPD-l,hSLE1,mPD-1,Programmed cell death 1,Programmed cell death protein 1,Programmed Death-1,SLEB2,Pd1,Pdcd1
- Anwendung:
- Block/Inhibit/Neutralise, Flow Cytometry
- Buffer:
- Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.
- translate.label.attr.clone:
- RMP1-14
- Klonalität:
- Monoclonal
- Konzentration:
- >= 1 mg/ml
- Weitere Details:
- Programmed cell death 1 (PD-1), also known as CD279, is a 55 kD member of the immunoglobulin superfamily. CD279 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) in the cytoplasmic region and plays a key role in peripheral tolerance and autoimmune disease. CD279 is expressed predominantly on activated T cells, B cells, and myeloid cells. PD-L1 (B7-H1) and PD-L2 (B7-DC) are ligands of CD279 (PD-1) and are members of the B7 gene family. Evidence suggests overlapping functions for these two PD-1 ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells. Interaction of CD279 ligands results in inhibition of T cell proliferation and cytokine secretion. None (Azide-Free,Low Endotoxin) are perfectly suited to be used in culture or in vivo (for nonhuman studies) for functional assays blocking, neutralizing, activation or depletion where the presence of azide may damage cells or exogenous endotoxin may signal or activate cells.
- Host:
- Rat
- Immunogen:
- Recombinant Human CD279 protein
- Isotyp:
- IgG2a, kappa
- Aufreinigung:
- protein a/g purified
- Reaktivitäten:
- Mouse
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 2-8[o]C Avoid freeze/thaw cycles., -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Monoclonal Antibody
- Datenblatt des Herstellers:p-purified_anti_mouse_cd279_antibody[rmp1_14],_functional_grade-an007850