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Antikörper

Purified Anti-Human IL-9 Antibody[MH9A4], Functional Grade

Produktgrößen
100 ug
£89,00
AN007820-100UG
1 mg
£171,00
AN007820-1MG
5 mg
£490,00
AN007820-5MG
25 mg
£1515,00
AN007820-25MG
50 mg
£2247,00
AN007820-50MG
100 mg
£3211,00
AN007820-100MG
Über dieses Produkt
SKU:
AN007820
Zusätzliche Namen:
Cytokine P,Interleukin,TCGF,IL9,HP40,IL-9,P40,Cytokine P40,Interleukin-9,P40 Cytokine,P40 T-cell and Mast Cell Growth Factor,T-cell Growth Factor P40,TCGF3,TCGFIII
Anwendung:
Flow Cytometry
Buffer:
Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.
translate.label.attr.clone:
MH9A4
Klonalität:
Monoclonal
Konzentration:
>= 1 mg/ml
Weitere Details:
IL-9 is a 14 kDa cytokine originally named P40 and identified by its proliferative effects on T cell populations. The receptor, which is a heterodimer of the gamma chain portion of the IL-2 receptor and the IL-9R chain, activates Jak/STAT signaling pathways upon binding its ligand. Since the discovery of IL-9, numerous other functions have been observed. It induces Th17 and Treg differentiation in CD4+ T cells, IgE production in B cells, and the differentiation and proliferation of mast cells. IL-9 expression was initially observed in Th2 cells, but has since been found in Th17, eosinophil, and mast cells. Th9 cells, a newly discovered subset of CD4+ T cells, are characterized by the secretion of large amounts of IL-9 and IL-10. Th9 development is induced by stimulation of undifferentiated CD4+ with IL-4 and TGF beta. Th2 cells can also be driven towards a Th9 phenotype in the presence of TGF beta. None (Azide-Free,Low Endotoxin) are perfectly suited to be used in culture or in vivo (for nonhuman studies) for functional assays blocking, neutralizing, activation or depletion where the presence of azide may damage cells or exogenous endotoxin may signal or activate cells.
Host:
Mouse
Immunogen:
Recombinant Human IL-9 protein
Isotyp:
IgG2b, kappa
Reinheit:
>98%
Aufreinigung:
protein a/g purified
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
2-8[o]C Avoid freeze/thaw cycles., -20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Monoclonal Antibody
HEK293T cells transfected with pcDNA3.1 plasmid encoding Human IL-9 gene were stained with 0.2 ug Purified Anti-Human IL-9 Antibody[MH9A4], Functional Grade (Right) and 0.2 ug Mouse IgG2b, K Kappa Isotype Control (Left), followed by Elab Fluor®647-conjugated Goat Anti-Mouse IgG Secondary Antibody.
Human peripheral blood lymphocytes were stained with 0.2 ug Purified Anti-Human CD4 Antibody[RPA-T4](Right) and 0.2 ug Mouse IgG1, K Kappa Isotype Control(Left), followed by PE-conjugated Goat Anti-Mouse IgG Secondary Antibody.
Human peripheral blood lymphocytes were stained with 0.2 ug AF/LE Purified Anti-Human CD4 Antibody[RPA-T4] (Right) and 0.2 ug Mouse IgG1, K Kappa Isotype Control (Left), followed by PE-conjugated Goat Anti-Mouse IgG Secondary Antibody.
Human peripheral blood lymphocytes were stained with 0.2 ug AF/LE Purified Anti-Human CD8a Antibody[OKT-8] (Right) and 0.2 ug Mouse IgG2a, K Kappa Isotype Control (Left), followed by Elab Fluor® 647-conjugated Goat Anti-Mouse IgG Secondary Antibody.
C57BL/6 Mouse bone marrow cells were stained with 0.2 ug AF/LE Purified Anti-Mouse Ly6G Antibody[1A8] (Right) and 0.2 ug Rat IgG2a, K Kappa Isotype Control (Left), followed by Elab Fluor® 647-conjugated Goat Anti-Rat IgG Secondary Antibody.