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Antikörper

Annexin A1 Polyclonal Antibody

Produktgrößen
25 ul
£134,00
AN007180L-25UL
100 ul
£291,00
AN007180L-100UL
Über dieses Produkt
SKU:
AN007180L
Zusätzliche Namen:
ANX;Annexin I (lipocortin I);AnnexinA1;AnnexinI;ANX 1;ANX A1;ANXA 1;ANXA1 protein;CalpactinII;Chromobindin9;HGNC:533;Lipocortin 1;lipocortin I;ANX1;LPC1;Annexin I;Annexin-1;Calpactin II;Calpactin-2;Chromobindin-9;Lipocortin I;Phospholipase A2 inhibitory protein;p35;Lipocortin1;LipocortinI;LPC 1;LPC;ANXA;Annexin A;ANXA1;ANX1;LPC1;Annexin 1;Calpactin 2;Chromobindin 9;Annexin-1;Chromobindin-9;p35;Calpactin-2;Annexin A1;Annexin I;Calpactin II;Lipocortin I;Phospholipase A2 Inhibitory Protein
Anwendung:
Western Blot
Buffer:
PBS with 0.05% proclin 300, 1% protective protein and 50% glycerol,pH7.4
Klonalität:
Polyclonal
Konzentration:
1 mg/ml
Weitere Details:
Plays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process. Has anti-inflammatory activity. Plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. Contributes to the adaptive immune response by enhancing signaling cascades that are triggered by T-cell activation, regulates differentiation and proliferation of activated T-cells. Promotes the differentiation of T-cells into Th1 cells and negatively regulates differentiation into Th2 cells.Has no effect on unstimulated T cells. Negatively regulates hormone exocytosis via activation of the formyl peptide receptors and reorganization of the actin cytoskeleton.Has high affinity for Ca2+ and can bind up to eight Ca2+ ions. Displays Ca2+-dependent binding to phospholipid membranes. Plays a role in the formation of phagocytic cups and phagosomes. Plays a role in phagocytosis by mediating the Ca2+-dependent interaction between phagosomes and the actin cytoskeleton.
Host:
Rabbit
Immunogen:
Recombinant Human Annexin A1 protein expressed by E.coli
Isotyp:
IgG
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human, Mouse, Rat
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Polyclonal Antibody