GRP78 Polyclonal Antibody
Produktgrößen
25 ul
£134,00
AN006780L-25UL
100 ul
£291,00
AN006780L-100UL
Über dieses Produkt
- SKU:
- AN006780L
- Zusätzliche Namen:
- 78 kDa glucose-regulated protein, BIP, Binding-immunoglobulin protein, Endoplasmic reticulum chaperone BiP, GRP, GRP-78, GRP78, HEL-S-89n, HSP70 family protein, HSP70 family protein 5, HSPA, HSPA5, Heat shock protein family A member, Immunoglobulin heavy chai, MIF, MIF2
- Anwendung:
- Western Blot
- Buffer:
- PBS with 0.05% Proclin300, 1% protective protein and 50% glycerol, pH7.4
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- GRP78 (Glucose-regulated protein 78 kDa, also BiP and HSPA5) is a 72 kDa member of the heat shock protein 70 family of proteins. Intracellularly, GRP78 is an endoplasmic reticulum chaperone that participates in protein folding, extracellularly, it induces IL-10 production from T cells and interacts with Cripto to block TGF-beta signaling. Human GRP78 precursor is 654 amino acids (aa) in length. It contains an 18 aa signal sequence and a 636 aa mature region that shows a hydantoinase A region (aa 145-245) and a C-terminal KDEL motif that is present on intracellular GRP78, but absent on secreted GRP78. There is alternative splicing in the signal sequence (aa 1-10), and multiple single aa substitituion. Over aa 1-654, human GRP78 is more than 97% aa identical to mouse and rat GRP78.
- Host:
- Rabbit
- Immunogen:
- Recombinant Human GRP78 protein expressed by E.coli
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-grp78_polyclonal_antibody-an006780l