Purified Anti-Human HLA-G Antibody[MEM-G/11]
Produktgrößen
25 ug
£80,00
AN006210P-25UG
100 ug
£118,00
AN006210P-100UG
Über dieses Produkt
- SKU:
- AN006210P
- Zusätzliche Namen:
- HLA,MHC-G,HLA-G,HLA-G HLA-6.0 HLAG,HLA-G5,HLA-6.0,HLAG,alpha chain G,B2 microglobulin,class I,DADB-15K14.8,HLA 6.0,HLA class I histocompatibility antigen,HLA class I histocompatibility antigen alpha chain G,HLA class I molecule,HLA G,HLA G antigen,HLA G histocompatibility antigen class I G,HLA G3,HLA60,HLA-G histocompatibility antigen,Major histocompatibility complex class I G,MHC class I antigen,MHC class I antigen G,MHC G,TCA,T-cell A locus
- Anwendung:
- Flow Cytometry
- Buffer:
- Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.
- translate.label.attr.clone:
- MEM-G/11
- Klonalität:
- Monoclonal
- Konzentration:
- >= 1 mg/ml
- Weitere Details:
- HLA-G Antibody (4H84) is an IgG1 K Kappa mouse monoclonal HLA-G antibody (also designated HLA major histocompatibility complex, class I, G antibody, human leukocyte antigen (HLA) G antibody, 45 kDa transmembrane class I human leukocyte antigen G antibody, chromosome 6p22 gene complex class 1G antibody, placenta trophoblast marker antibody, or fetal derived placental cell marker antibody) that detects the HLA-G protein of mouse, rat and human origin by WB, IP, IF and IHC(P). HLA-G Antibody (4H84) is available as both the non-conjugated anti-HLA-G antibody form, as well as multiple conjugated forms of anti-HLA-G antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Major histocompatibility complex (MHC), human leukocyte antigen (HLA) molecules are cell-surface receptors that bind foreign peptides and present them to T lymphocytes. MHC class I molecules consist of two polypeptide chains, an A Alpha or heavy chain, and a non-covalently associated protein, B Beta-2-microglobulin. Cytotoxic T lymphocytes bind antigenic peptides presented by MHC class I molecules. Antigens that bind to MHC class I molecules are typically 8-10 residues in length and are stabilized in a peptide binding groove. MHC class II molecules are encoded by polymorphic MHC genes and consist of a non-covalent complex of an a and b chain. Helper T lymphocytes bind antigenic peptides presented by MHC class II molecules. MHC class II molecules bind 13-18 amino acid antigenic peptides. Accumulating in endosomal/lysosomal compartments and on the surface of B cells, HLA-DM and -DO molecules regulate binding of exogenous peptides to class II molecules (HLA-DR) by sustaining a conformation that favors peptide exchange. The differential structural properties of MHC class I and class II molecules account for their respective roles in activating different populations of T lymphocytes.
- Host:
- Mouse
- Immunogen:
- Recombinant Human HLA-G protein
- Isotyp:
- IgG1, kappa
- Reinheit:
- >98%
- Aufreinigung:
- protein a/g purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 2-8[o]C Avoid freeze/thaw cycles., -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Monoclonal Antibody
- Datenblatt des Herstellers:11]-an006210p