ANGPTL4 Polyclonal antibody
Produktgrößen
25 ul
£134,00
AN006110L-25UL
100 ul
£291,00
AN006110L-100UL
Über dieses Produkt
- SKU:
- AN006110L
- Zusätzliche Namen:
- ARP;Secreted protein Bk;Angiopoietin-like protein;Angiopoietin-related protein;ANGPTL;425O18;425O18-1;Angiopoietin-like protein 4;Angiopoietin-related protein 4;ARP4;Fasting-induced adipose factor;Hepatic fibrinogen/angiopoietin-related protein;HFARP;NL2;PGAR;pp1158;Secreted protein Bk89;Farp;Fiaf;Ng27;Angptl4
- Anwendung:
- Western Blot
- Buffer:
- PBS
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- Angiopoietin-related protein 4 (ANGPTL4) is a secreted protein and contains 1 fibrinogen C-terminal domain. The protein may act as a regulator of angiogenesis and modulate tumorigenesis. It inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. ANGPTL4 may exert a protective function on endothelial cells through an endocrine action. It is directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity (By similarity). In response to hypoxia, the unprocessed form of the protein accumulates in the subendothelial extracellular matrix (ECM). The matrix-associated and immobilized unprocessed form limits the formation of actin stress fibers and focal contacts in the adhering endothelial cells and inhibits their adhesion. It also decreases motility of endothelial cells and inhibits the sprouting and tube formation.
- Host:
- Rabbit
- Immunogen:
- Recombinant Mouse ANGPTL4 protein expressed by Mammalian
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-angptl4_polyclonal_antibody-an006110l