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Antikörper

Ki67 Monoclonal Antibody

Produktgrößen
25 ul
£134,00
AN005400L-25UL
100 ul
£291,00
AN005400L-100UL
Über dieses Produkt
SKU:
AN005400L
Zusätzliche Namen:
MIB,MKI,marker of proliferation Ki,Proliferation marker protein Ki,Antigen identified by monoclonal antibody Ki,PPP1R,MKI67,KIA,MIB-,MIB-1,PPP1R105,marker of proliferation Ki-67,Ki67,Antigen identified by monoclonal antibody Ki-67,Antigen Ki67,Antigen KI-67,Proliferation marker protein Ki-67,Antigen identified by monoclonal Ki 67,Antigen identified by monoclonal Ki-67,MIB 1,Proliferation related Ki 67 antigen,Protein phosphatase 1 regulatory subunit 105,RP11-380J17.2
Anwendung:
Immunofluorescence, Immunohistochemistry
Buffer:
PBS with 0.05% Proclin300, 1% protective protein and 50% glycerol, pH7.4
translate.label.attr.clone:
3B7
Klonalität:
Monoclonal
Konzentration:
1 mg/ml
Weitere Details:
Required to maintain individual mitotic chromosomes dispersed in the cytoplasm following nuclear envelope disassembly. Associates with the surface of the mitotic chromosome, the perichromosomal layer, and covers a substantial fraction of the chromosome surface. Prevents chromosomes from collapsing into a single chromatin mass by forming a steric and electrostatic charge barrier: the protein has a high net electrical charge and acts as a surfactant, dispersing chromosomes and enabling independent chromosome motility. Binds DNA, with a preference for supercoiled DNA and AT-rich DNA. Does not contribute to the internal structure of mitotic chromosomes. May play a role in chromatin organization. It is however unclear whether it plays a direct role in chromatin organization or whether it is an indirect consequence of its function in maintaining mitotic chromosomes dispersed (Probable).
Host:
Mouse
Immunogen:
Recombinant human Ki67 protein expressed by E.coli
Isotyp:
IgG1
Aufreinigung:
Protein A/G Purification
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Monoclonal Antibody