Ki67 Polyclonal Antibody
Produktgrößen
25 ul
£134,00
AN004340L-25UL
100 ul
£291,00
AN004340L-100UL
Über dieses Produkt
- SKU:
- AN004340L
- Zusätzliche Namen:
- MIB,MKI,marker of proliferation Ki,Proliferation marker protein Ki,Antigen identified by monoclonal antibody Ki,PPP1R,MKI67,KIA,MIB-,MIB-1,PPP1R105,marker of proliferation Ki-67,Ki67,Antigen identified by monoclonal antibody Ki-67,Antigen Ki67,Antigen KI-67,Proliferation marker protein Ki-67,Antigen identified by monoclonal Ki 67,Antigen identified by monoclonal Ki-67,MIB 1,Proliferation related Ki 67 antigen,Protein phosphatase 1 regulatory subunit 105,RP11-380J17.2
- Anwendung:
- Immunohistochemistry
- Buffer:
- PBS with 0.05% Proclin300, 1% protective protein and 50% glycerol, pH7.4
- Klonalität:
- Polyclonal
- Konzentration:
- 1 mg/ml
- Weitere Details:
- Required to maintain individual mitotic chromosomes dispersed in the cytoplasm following nuclear envelope disassembly. Associates with the surface of the mitotic chromosome, the perichromosomal layer, and covers a substantial fraction of the chromosome surface. Prevents chromosomes from collapsing into a single chromatin mass by forming a steric and electrostatic charge barrier: the protein has a high net electrical charge and acts as a surfactant, dispersing chromosomes and enabling independent chromosome motility. Binds DNA, with a preference for supercoiled DNA and AT-rich DNA. Does not contribute to the internal structure of mitotic chromosomes. May play a role in chromatin organization. It is however unclear whether it plays a direct role in chromatin organization or whether it is an indirect consequence of its function in maintaining mitotic chromosomes dispersed (Probable).
- Host:
- Rabbit
- Immunogen:
- Recombinant Human Ki67 protein expressed by E.coli
- Isotyp:
- IgG
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:p-ki67_polyclonal_antibody-an004340l