FITC Anti-Human CD8 Antibody[UCHT-4]
Produktgrößen
20 tests
£64,00
AN00427C-20TESTS
100 tests
£89,00
AN00427C-100TESTS
2 x 100 tests
£120,00
AN00427C-2X100TESTS
Über dieses Produkt
- SKU:
- AN00427C
- Zusätzliche Namen:
- T8;Leu2
- Anwendung:
- Flow Cytometry
- Buffer:
- PBS
- translate.label.attr.clone:
- UCHT-4
- Klonalität:
- Monoclonal
- Konjugat:
- FITC
- Konzentration:
- 5 ul/test
- Weitere Details:
- CD8a is a 32-34 kD type I glycoprotein. It forms a homodimer (CD8a/a) or heterodimer (CD8a/b) with CD8b. CD8, also known as T8 and Leu2, is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers). CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation and has been shown to play a role in thymic differentiation. Two domains in CD8a are important for function: the extracellular IgSF domain binds the A Alpha3 domain of MHC class I and the cytoplasmic CXCP motif binds the tyrosine kinase p56 Lck
- Host:
- Mouse
- Immunogen:
- CD8
- Isotyp:
- IgG1, kappa
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 2-8[o]C Do not freeze. Protect from light.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Monoclonal Antibody
- Datenblatt des Herstellers:p-fitc_anti_human_cd8_antibody[ucht_4]-an00427c