APC Anti-Human/Mouse Integrin B Beta7 Antibody[FIB21]
Produktgrößen
20 tests
£141,00
AN00423E-20TESTS
100 tests
£285,00
AN00423E-100TESTS
2 x 100 tests
£472,00
AN00423E-2X100TESTS
Über dieses Produkt
- SKU:
- AN00423E
- Zusätzliche Namen:
- B Beta7 Integrin;integrin B Betap;ITGB7
- Anwendung:
- Flow Cytometry
- Buffer:
- PBS
- translate.label.attr.clone:
- FIB21
- Klonalität:
- Monoclonal
- Konjugat:
- APC
- Konzentration:
- 5 ul/test
- Weitere Details:
- Integrin B Beta7 is a 130 kD glycoprotein also known as integin B Betap. It is a member of the Ig superfamily. In association with integrin A Alpha4 or A AlphaE chain, B Beta7 forms A Alpha4/B Beta7 or A AlphaE/B Beta7 heterodimer. A Alpha4/B Beta7 (CD49d/B Beta7, LPAM-1) is expressed on the majority of peripheral lymphocytes, on small subsets of thymocytes, and bone marrow progenitors. LPAM-1 binds to several ligands, VCAM-1, MAdCAM-1 and fibronectin, and is involved in lymphocyte adhesion and some hematopoietic progenitor cells migration. A AlphaE/B Beta7 (CD103/B Beta7,A AlphaIEL/B Beta7) is expressed on intestinal intraepithelial lymphocytes (IEL), dendritic epidermal T cells, T regulatory cells, a subset of CD8+ T cells in lymph nodes and lamina propria. CD103/B Beta7 complex is thought to play a role in lymphocyte retention via interaction with its ligand E-Cadherin.
- Host:
- Rat
- Immunogen:
- Integrin β7
- Isotyp:
- IgG2b, kappa
- Reaktivitäten:
- Human, Mouse
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 2-8[o]C Do not freeze. Protect from light.
- Hersteller:
- Elabscience
- Typ:
- Antibody: Monoclonal Antibody
- Datenblatt des Herstellers:mouse_integrin_β7_antibody[fib21]-an00423e