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Antikörper

Purified Anti-Human HLA-G Antibody[87G], Functional Grade

Produktgrößen
100 ug
£89,00
AN002910-100UG
1 mg
£171,00
AN002910-1MG
5 mg
£490,00
AN002910-5MG
25 mg
£1515,00
AN002910-25MG
50 mg
£2247,00
AN002910-50MG
100 mg
£3211,00
AN002910-100MG
Über dieses Produkt
SKU:
AN002910
Zusätzliche Namen:
HLA,MHC-G,HLA-G,HLA-G HLA-6.0 HLAG,HLA-G5,HLA-6.0,HLAG,alpha chain G,B2 microglobulin,class I,DADB-15K14.8,HLA 6.0,HLA class I histocompatibility antigen,HLA class I histocompatibility antigen alpha chain G,HLA class I molecule,HLA G,HLA G antigen,HLA G histocompatibility antigen class I G,HLA G3,HLA60,HLA-G histocompatibility antigen,Major histocompatibility complex class I G,MHC class I antigen,MHC class I antigen G,MHC G,TCA,T-cell A locus
Anwendung:
Flow Cytometry
Buffer:
Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.
translate.label.attr.clone:
87G
Klonalität:
Monoclonal
Konzentration:
>= 1 mg/ml
Weitere Details:
HLA-G Antibody (4H84) is an IgG1 K Kappa mouse monoclonal HLA-G antibody (also designated HLA major histocompatibility complex, class I, G antibody, human leukocyte antigen (HLA) G antibody, 45 kDa transmembrane class I human leukocyte antigen G antibody, chromosome 6p22 gene complex class 1G antibody, placenta trophoblast marker antibody, or fetal derived placental cell marker antibody) that detects the HLA-G protein of mouse, rat and human origin by WB, IP, IF and IHC(P). HLA-G Antibody (4H84) is available as both the non-conjugated anti-HLA-G antibody form, as well as multiple conjugated forms of anti-HLA-G antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Major histocompatibility complex (MHC), human leukocyte antigen (HLA) molecules are cell-surface receptors that bind foreign peptides and present them to T lymphocytes. MHC class I molecules consist of two polypeptide chains, an A Alpha or heavy chain, and a non-covalently associated protein, B Beta-2-microglobulin. Cytotoxic T lymphocytes bind antigenic peptides presented by MHC class I molecules. Antigens that bind to MHC class I molecules are typically 8-10 residues in length and are stabilized in a peptide binding groove. MHC class II molecules are encoded by polymorphic MHC genes and consist of a non-covalent complex of an a and b chain. Helper T lymphocytes bind antigenic peptides presented by MHC class II molecules. MHC class II molecules bind 13-18 amino acid antigenic peptides. Accumulating in endosomal/lysosomal compartments and on the surface of B cells, HLA-DM and -DO molecules regulate binding of exogenous peptides to class II molecules (HLA-DR) by sustaining a conformation that favors peptide exchange. The differential structural properties of MHC class I and class II molecules account for their respective roles in activating different populations of T lymphocytes. None (Azide-Free,Low Endotoxin) are perfectly suited to be used in culture or in vivo (for nonhuman studies) for functional assays blocking, neutralizing, activation or depletion where the presence of azide may damage cells or exogenous endotoxin may signal or activate cells.
Host:
Mouse
Immunogen:
Recombinant Human HLA-G protein
Isotyp:
IgG2a, kappa
Reinheit:
>98%
Aufreinigung:
protein a/g purified
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
2-8[o]C Avoid freeze/thaw cycles., -20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Monoclonal Antibody
JEG3 were stained with 0.2 ug AF/LE Purified Anti-Human HLA-G Antibody[87G] (Right) and 0.2 ug Mouse IgG2a, K Kappa Isotype Control (Left), followed by FITC-conjugated Goat Anti-Mouse IgG Secondary Antibody.
C57BL/6 thymocytes sequentially were stained with CD4 Biotin, Streptavidin, then 0.2 ug Purified Anti-Streptavidin Antibody[16D11] (Right) and 0.2 ug Rat IgG1, K Kappa Isotype Control (Left), followed by FITC-conjugated Goat Anti-Rat IgG Secondary Antibody.
C57BL/6 thymocytes sequentially were stained with CD4 Biotin, Streptavidin, then 0.2 ug Purified Anti-Streptavidin Antibody[15E6] (Right) and 0.2 ug Mouse IgG1, K Kappa Isotype Control (Left), followed by FITC-conjugated Goat Anti-Mouse IgG Secondary Antibody.
Human peripheral blood monocytes were stained with 0.2 ug Purified Anti-Human CD14 Monoclonal Antibody[UCHM-1](Right) and 0.2 ug Mouse IgG2a, K Kappa Isotype Control(Left), followed by Elab Fluor® 647-conjugated Goat Anti-Mouse IgG Secondary Antibody.
C57/BL6 Mouse splenocytes were stained with 0.2 ug Biotin conjugated Anti-Mouse MHC I (H-2Kd) Antibody[SF1-1.1.10] (Right) and 0.2 ug Biotin conjugated Mouse IgG2a, K Kappa Isotype Control (Left), followed by Elab Fluor® 647-conjugated SA Secondary Antibody.