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Antikörper

AF/LE Purified Anti-Human HLA-G Antibody[87G]

Produktgrößen
25 ug
£66,00
AN002910-25UG
100 ug
£89,00
AN002910-100UG
1 mg
£171,00
AN002910-1MG
5 mg
£490,00
AN002910-5MG
25 mg
£1515,00
AN002910-25MG
50 mg
£2247,00
AN002910-50MG
100 mg
£3211,00
AN002910-100MG
Über dieses Produkt
SKU:
AN002910
Zusätzliche Namen:
HLA;MHC-G;HLA-G;HLA-G HLA-6.0 HLAG;HLA-G5;HLA-6.0;HLAG;alpha chain G;B2 microglobulin;class I;DADB-15K14.8;HLA 6.0;HLA class I histocompatibility antigen;HLA class I histocompatibility antigen alpha chain G;HLA class I molecule;HLA G;HLA G antigen;HLA G histocompatibility antigen class I G;HLA G3;HLA60;HLA-G histocompatibility antigen;Major histocompatibility complex class I G;MHC class I antigen;MHC class I antigen G;MHC G;TCA;T-cell A locus
Anwendung:
Flow Cytometry
Buffer:
Sterile PBS, pH 7.2. < 1.0 EU per mg of the antibody as determined by the LAL method.
translate.label.attr.clone:
87G
Klonalität:
Monoclonal
Konzentration:
>= 1 mg/ml
Weitere Details:
HLA-G Antibody (4H84) is an IgG1 K Kappa mouse monoclonal HLA-G antibody (also designated HLA major histocompatibility complex, class I, G antibody, human leukocyte antigen (HLA) G antibody, 45 kDa transmembrane class I human leukocyte antigen G antibody, chromosome 6p22 gene complex class 1G antibody, placenta trophoblast marker antibody, or fetal derived placental cell marker antibody) that detects the HLA-G protein of mouse, rat and human origin by WB, IP, IF and IHC(P). HLA-G Antibody (4H84) is available as both the non-conjugated anti-HLA-G antibody form, as well as multiple conjugated forms of anti-HLA-G antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Major histocompatibility complex (MHC), human leukocyte antigen (HLA) molecules are cell-surface receptors that bind foreign peptides and present them to T lymphocytes. MHC class I molecules consist of two polypeptide chains, an A Alpha or heavy chain, and a non-covalently associated protein, B Beta-2-microglobulin. Cytotoxic T lymphocytes bind antigenic peptides presented by MHC class I molecules. Antigens that bind to MHC class I molecules are typically 8-10 residues in length and are stabilized in a peptide binding groove. MHC class II molecules are encoded by polymorphic MHC genes and consist of a non-covalent complex of an a and b chain. Helper T lymphocytes bind antigenic peptides presented by MHC class II molecules. MHC class II molecules bind 13-18 amino acid antigenic peptides. Accumulating in endosomal/lysosomal compartments and on the surface of B cells, HLA-DM and -DO molecules regulate binding of exogenous peptides to class II molecules (HLA-DR) by sustaining a conformation that favors peptide exchange. The differential structural properties of MHC class I and class II molecules account for their respective roles in activating different populations of T lymphocytes.
Host:
Mouse
Immunogen:
HLA-G|Recombinant Human HLA-G protein
Isotyp:
IgG2a, kappa
Reinheit:
>98%
Aufreinigung:
protein a/g purified
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
2-8[o]C Avoid freeze/thaw cycles., -20[o]C Avoid freeze/thaw cycles.
Hersteller:
Elabscience
Typ:
Antibody: Monoclonal Antibody
  • Datenblatt des Herstellers:RKRlyL
C57BL/6 thymocytes sequentially were stained with CD4 Biotin, Streptavidin, then 0.2 ug Purified Anti-Streptavidin Antibody[16D11] (Right) and 0.2 ug Rat IgG1, K Kappa Isotype Control (Left), followed by FITC-conjugated Goat Anti-Rat IgG Secondary Antibody.
C57BL/6 thymocytes sequentially were stained with CD4 Biotin, Streptavidin, then 0.2 ug Purified Anti-Streptavidin Antibody[16D11] (Right) and 0.2 ug Rat IgG1, K Kappa Isotype Control (Left), followed by FITC-conjugated Goat Anti-Rat IgG Secondary Antibody.
C57BL/6 thymocytes sequentially were stained with CD4 Biotin, Streptavidin, then 0.2 ug Purified Anti-Streptavidin Antibody[15E6] (Right) and 0.2 ug Mouse IgG1, K Kappa Isotype Control (Left), followed by FITC-conjugated Goat Anti-Mouse IgG Secondary Antibody.
Human peripheral blood monocytes were stained with 0.2 ug Purified Anti-Human CD14 Monoclonal Antibody[UCHM-1](Right) and 0.2 ug Mouse IgG2a, K Kappa Isotype Control(Left), followed by Elab Fluor® 647-conjugated Goat Anti-Mouse IgG Secondary Antibody.
C57/BL6 Mouse splenocytes were stained with 0.2 ug Biotin conjugated Anti-Mouse MHC I (H-2Kd) Antibody[SF1-1.1.10] (Right) and 0.2 ug Biotin conjugated Mouse IgG2a, K Kappa Isotype Control (Left), followed by Elab Fluor® 647-conjugated SA Secondary Antibody.