PI(4,5)P2 PolyPIPosomes
Produktgrößen
100 ul
£465,00
ECH-Y-P045-100UL
250 ul
£1004,00
ECH-Y-P045-250UL
1 ml
£3548,00
ECH-Y-P045-1ML
Über dieses Produkt
- SKU:
- ECH-Y-P045
- Weitere Details:
- PolyPIPosomes are polymerized liposomes that show markedly increased stability (up to 6 months) vs. conventional liposomes. A biotin tag is incorporated for easy detection of PIPn-binding proteins with streptavidin reagents. \n- Uniform size (~200 nm) \n- Ready-to-use suspensions, no liposome preparation \nPolyPIPosomes have demonstrated utility in a number of assay formats: \n \n Protein pull-down \n Surface Plasmon Resonance \n Liposome overlay assay \n \n \n \n \nPI(4,5)P2 PolyPIPosomes are provided as a 1mM total lipid solution containing 5% PI(4,5)P2. Each order of 250 uL or 1 mL of PolyPIPosomes includes 100 uL of Control PolyPIPosomes. \nFeatured in Publications \n1) Ferguson, C. G., R. D. James, et al. (2005). "Phosphoinositide-Containing Polymerized Liposomes: Stable Membrane-Mimetic Vesicles for Protein-Lipid Binding Analysis." Bioconjug Chem 16(6): 1475-1483. \n2) Elkin, S. K., D. Ivanov, et al. (2005). "A PHD finger motif in the C-terminus of RAG2 modulates recombination activity." J Biol Chem 280(31): 28701-10. \n3) Mustafa, A. K., D. B. van Rossum, et al. (2009). "Glutamatergic regulation of serine racemase via reversal of PIP2 inhibition." Proc Natl Acad Sci U S A 106(8): 2921-6. \n4) Zemskov, E. A., I. Mikhailenko, et al. (2011). "Unconventional secretion of tissue transglutaminase involves phospholipid-dependent delivery into recycling endosomes." PLoS One 6(4): e19414. \n5) Tan, X., Y. Sun, et al. (2015). "LAPTM4B is a PtdIns(4,5)P2 effector that regulates EGFR signaling, lysosomal sorting, and degradation." Embo J 34(4): 475-90. \n \nBeing bio-reactive blog: "Lipid-Ligand interaction tools: lipids are not scary intermediates anymore" \n \n \n \nDocuments \nTechnical Data Sheet, Echelon
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- Please refer to datasheet
- Hersteller:
- Echelon Biosciences
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
