S1P Fluorescein
Produktgrößen
50 ug
£801,00
ECH-S-200F-50UG
Über dieses Produkt
- SKU:
- ECH-S-200F
- Weitere Details:
- Echelon offers a unique selection of sphingosine 1-phosphate analogs labeled at the terminus of the alkyl chain with biotin or fluorescent groups. All compounds have the natural erythro stereochemistry and are synthesized from chiral precursors. \n \n \n \nStorage \nSphingosine 1-phosphate fluorescein (S1P fluorescein) is relatively stable at room temperature as a solid. It is best stored as a dried solid, protected from light at -20 °C. Solutions/emulsions should be kept at -20 °C. Storage in basic buffers (pH > 9.0) or acidic buffers (pH < 4.0) may cause decomposition. \nExcitation/Emission \n494/521 nm \nSolubility \nMeOH >1 mg/ml \nFeatured in Publications \n1) Peest, U., S. C. Sensken, et al. (2008). "S1P-lyase independent clearance of extracellular sphingosine 1-phosphate after dephosphorylation and cellular uptake." J Cell Biochem 104(3): 756-72. \n2) Meissner, A., J. Yang, et al. (2012). "Tumor Necrosis Factor-A Alpha-Mediated Downregulation of the Cystic Fibrosis Transmembrane Conductance Regulator Drives Pathological Sphingosine-1-Phosphate Signaling in a Mouse Model of Heart Failure." Circulation 125(22): 2739-2750. \n3) Vogt, K., et al. (2018). "Release of Platelet-Derived Sphingosine-1-Phosphate Involves Multidrug Resistance Protein 4 (MRP4/ABCC4) and Is Inhibited by Statins." Thromb Haemost 118(01): 132-142. \n \nBulk quantities of this product are available. Please email echelon@echelon-inc.com for more information. \n \n \n \nDocuments \nTechnical Data Sheet, Echelon
- Versandbedingungen:
- Dry Ice
- Lagerbedingungen:
- Please refer to datasheet
- Hersteller:
- Echelon Biosciences
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules
