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Produktgrößen
100 ug
£310,00
ECH-P-3900-100UG
500 ug
£700,00
ECH-P-3900-500UG
1 mg
£1118,00
ECH-P-3900-1MG
Über dieses Produkt
SKU:
ECH-P-3900
Weitere Details:
GroPI(3,4,5)P3 (Glycerophosphoinositol 3,4,5-triphosphate) is a synthetic phosphoinositide without acyl chains on the 1- & 2-positions of the glycerol. \n \nPhosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 3,4,5-trisphosphate (PIP3), formed from PI(4,5)P2 though phosphorylation by PI 3-kinase, activates numerous signaling pathways resulting in cell proliferation, growth, survival, glucose transport and protein synthesis. High PIP3 levels from disregulation of PI3-K have been demonstrated in cancer and inflammatory diseases. PIP3 is hydrolyzed by the phosphatases PTEN to PI(4,5)P2 and SHIP to PI(3,4)P2. Glycerophosphoinositol 3,4,5-triphosphate (GroPIP3) is missing the acyl chains from the 1- & 2-positions of the glycerol. \n \n \n \nStorage \n-20 °C \n \n \n \nDocuments \nTechnical Data Sheet, Echelon
Versandbedingungen:
Dry Ice
Lagerbedingungen:
Please refer to datasheet
Hersteller:
Echelon Biosciences
Typ:
Proteins, Peptides, Small Molecules & Other Biomolecules: Small Molecules