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Proteine und Peptide

ZSTK474 (PI3K Inhibitor)

Produktgrößen
5 mg
£137,00
ECH-B-0307-5MG
25 mg
£298,00
ECH-B-0307-25MG
100 mg
£635,00
ECH-B-0307-100MG
Über dieses Produkt
SKU:
ECH-B-0307
Weitere Details:
ZSTK474 is a potent inhibitor of all four isoforms of class I PI 3-kinase (A Alpha 6.7 nM, B Beta 10.4 nM, G Gamma 11.7 nM, D Delta 1.8 nM). It binds to the ATP-binding pocket and is more active and less toxic than LY294002. ZSTK474 shows anti-tumor activity against human xenografts (A549, PC-3, WiDr) in mice by arresting cell growth. In addition, it was able to inhibit osteoclast formation and collagen-induced arthritis in a mouse model. \n \n \n \nStorage \n-20°C \n \n \n \nDocuments \nTechnical Data Sheet, Echelon
Versandbedingungen:
Ambient
Lagerbedingungen:
Please refer to datasheet
Hersteller:
Echelon Biosciences
Typ:
Proteins, Peptides, Small Molecules & Other Biomolecules: Inhibitors