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Proteine und Peptide

MG-115 (Proteasome Inhibitor)

Produktgrößen
5 mg
£304,00
ECH-882-10-5MG
Über dieses Produkt
SKU:
ECH-882-10
CAS Number:
133407-86-0
Weitere Details:
CAS Number: 133407-86-0 \nMolecular Weight: 461.29 \nSalt Form: N/A \nPurity: >96% \nSequence (3-letter): Z-Leu-Leu-Nva-CHO \nSequence (1-letter): Z-LL(Nva)-CHO \nStorage: -20 ?C or below \n \nMG-115 (Z-Leu-Leu-Nva-CHO) is a potent, cell permeable inhibitor of the 20S proteosome. It forms a reversible hemiacetal adduct and can also inhibit cathepsins and calpains. It reduces degradation of ubiquitinated proteins and blocks proteolytic conversion of protein precursors. MG-115 is known to induce the heat shock response and apoptosis. \nReferences \nRock, K.L., Gramm, C., Rothstein, L.,?et al. (1994) "Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules".?Cell?78,?761-771., Echelon
Molekulargewicht:
461.29
Sequenz:
Z-Leu-Leu-Nva-CHO \n
Versandbedingungen:
Ambient
Lagerbedingungen:
-20[o]C
Hersteller:
Echelon Biosciences
Typ:
Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides