Caspase 3 (Apopain) Inhibitor
Produktgrößen
5 mg
£370,00
ECH-864-20-5MG
Über dieses Produkt
- SKU:
- ECH-864-20
- CAS Number:
- 184179-08-6
- Weitere Details:
- CAS Number: 184179-08-6 \nMolecular Weight: 502.19 \nSalt Form: N/A \nPurity: >96% \nSequence (3-letter): Ac-Asp-Glu-Val-Asp-CHO \nSequence (1-letter): Ac-DEVD-CHO \nStorage: -20 ?C or below \nSolubility: 13.7 mg/ml in DMSO \n \nCaspase-3 (Apopain) is commonly activated by numerous death signals and cleaves a variety of important cellular proteins and is essential for brain development. Ac-DEVD-CHO is a potent, reversible inhibitor of caspase-3 (Ki < 1nM for purified caspase-3) and also inhibits caspase-7 (Ki = 1.6 nM) as well as other caspases to a lesser extent. \nReferences \n1. Talanian, R.V. et al (1997) ?Substrate Specificities of Caspase Family Proteases? 272 (15): 9677?9682. \n2. Godinat, A. et al. (2013) ?A Biocompatible in Vivo Ligation Reaction and Its Application for Noninvasive Bioluminescent Imaging of Protease Activity in Living Mice? ACS Chemical Biology 8 (5): 987-999., Echelon
- Molekulargewicht:
- 502.19
- Sequenz:
- Ac-Asp-Glu-Val-Asp-CHO \n
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Echelon Biosciences
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
- Datenblatt des Herstellers:https://www.echelon-inc.com/product/ac-asp-glu-val-asp-cho-caspase-3-apopain-inhibitor/
