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Proteine und Peptide

Caspase 1 (ICE) Inhibitor

Produktgrößen
5 mg
£370,00
ECH-864-15-5MG
Über dieses Produkt
SKU:
ECH-864-15
CAS Number:
143313-51-3
Weitere Details:
CAS Number: 143313-51-3 \nMolecular Weight: 492.22 \nSalt Form: N/A \nPurity: >96% \nSequence (3-letter): Ac-Tyr-Val-Ala-Asp-CHO \nSequence (1-letter): Ac-YVAD-CHO \nStorage: -20 ?C or below \nSolubility: DMSO (5 mg/ml), water (5 mg/ml), ethanol (30 mg/ml), DMF (30 mg/ml) \n \nN-Ac-Tyr-Val-Ala-Asp-CHO (Ac-YVAD-CHO) is a synthetic peptide that reversibly and selectively inhibits interleukin-1? converting enzyme (ICE; Caspase-1). Caspase-1 is a pro-inflammatory cytokine and like other caspase inhibitors, interferes with the initiation of apoptosis and has numerous possible clinical applications \nReferences \n1. Cerretti D.P., et al. (1992) ?Molecular cloning of the interleukin-1 beta converting enzyme? Science 256: 97?100. \n2.Thornberry N.A. et al. (1992) ?A novel heterodimeric cysteine protease is required for interleukin-1 beta processing in monocytes? Nature 356: 768?774., Echelon
Molekulargewicht:
492.22
Sequenz:
Ac-Tyr-Val-Ala-Asp-CHO \n
Versandbedingungen:
Ambient
Lagerbedingungen:
-20[o]C
Hersteller:
Echelon Biosciences
Typ:
Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides