Ac-Val-Asp-Gln-Gln-Asp-pNA (Caspase 2 (ICH-1) Substrate)
Produktgrößen
5 mg
£219,00
ECH-860-44-5MG
25 mg
£598,00
ECH-860-44-25MG
Über dieses Produkt
- SKU:
- ECH-860-44
- Weitere Details:
- Molecular Weight: 765.29 \nSalt Form: TFA \nPurity: >96% \nSequence (3-letter): Ac-Val-Asp-Gln-Gln-Asp-pNA \nSequence (1-letter): Ac-VDQQD-pNA \nStorage: -20 ?C or below \n \nAc-Val-Asp-Gln-Gln-Asp-pNA is a colorimetric substrate for Caspase 2. Caspase 2, part of the ICH-1 sub-family, is a cysteine protease with a poorly defined role in apoptosis. It associates with several apoptotic proteins such as death effector filament-forming Ced-4-like apoptosis protein (DEFCAP), RIP-associated Ich-1/Ced-3-homologue protein with a death domain (RAIDD), and apoptosis repressor with caspase recruitment domain (ARC). Caspase 2 can be activated by the PIDDosome formed by the association of PIDD1 and CRADD. Recent work demonstrates that Caspase-2 resides in the mitochondria and is essential for stress-induced apoptosis. \n \nActivity is quantified by the release of p-nitroaniline which is measured by absorbance at 405 nm., Echelon
- Molekulargewicht:
- 765.29
- Sequenz:
- Ac-Val-Asp-Gln-Gln-Asp-pNA \n
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Echelon Biosciences
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
- Datenblatt des Herstellers:https://www.echelon-inc.com/product/ac-val-asp-gln-gln-asp-pna-caspase-2-ich-1-substrate-colorimetric/
