Caspase 1 (ICE) Substrate
Produktgrößen
5 mg
£275,00
ECH-860-41-5MG
25 mg
£816,00
ECH-860-41-25MG
Über dieses Produkt
- SKU:
- ECH-860-41
- Weitere Details:
- Molecular Weight: 723.28 \nSalt Form: N/A \nPurity: >96% \nSequence (3-letter): Ac-Tyr-Glu-Val-Asp-AMC \nSequence (1-letter): Ac-YEVD-AMC \nStorage: -20 ?C or below \n \nAc-Tyr-Glu-Val-Asp-AMC is a fluorogenic substrate for Caspase 1. Caspase 1/Interleukin 1b converting enzyme (ICE) is a cysteine protease that cleaves specifically at aspartic acid. ICE converts inactive IL-1 beta precursor to a pro-inflammatory cytokine that mediates a wide range of immune and inflammatory response. ICE-related cysteine proteases are required for E1A-induced, p53-dependent apoptosis in baby rat kidney (BRK) cells. Adenovirus E1B 19K protein, which is a potent inhibitor of apoptosis, inhibits activation of these proteases in BRK cells. \n \nActivity is quantified by release of free fluorescent 7-amino-4-methylcoumarin (AMC) which excites at 360-380 nm and emits at 440-460 nm., Echelon
- Molekulargewicht:
- 723.28
- Sequenz:
- Ac-Tyr-Glu-Val-Asp-AMC \n
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Echelon Biosciences
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
- Datenblatt des Herstellers:https://www.echelon-inc.com/product/ac-tyr-glu-val-asp-amc-caspase-1-ice-substrate-fluorogenic/
