Ac-Tyr-Val-Ala-Asp-AMC (Caspase 1 (ICE) Substrate, fluorogenic)
Produktgrößen
5 mg
£275,00
ECH-860-16-5MG
25 mg
£816,00
ECH-860-16-25MG
Über dieses Produkt
- SKU:
- ECH-860-16
- CAS Number:
- 149231-65-2
- Weitere Details:
- CAS Number: 149231-65-2 \nMolecular Weight: 665.27 \nSalt Form: N/A \nPurity: >96% \nSequence (3-letter): Ac-Tyr-Val-Ala-Asp-AMC \nSequence (1-letter): Ac-YVAD-AMC \nStorage: -20 ?C or below \n \nCaspase 1 (ICE) Substrate (Ac-Tyr-Val-Ala-Asp-AMC) is a fluorogenic substrate for interleukin 1b converting enzyme (ICE) which is a cysteine protease that cleaves specifically at aspartic acid. ICE converts inactive IL-1 beta precursor to a pro-inflammatory cytokine that mediates a wide range of immune and inflammatory response. ICE-related cysteine proteases are required for E1A-induced, p53-dependent apoptosis in baby rat kidney (BRK) cells. Adenovirus E1B 19K protein, which is a potent inhibitor of apoptosis, inhibits activation of these proteases in BRK cells. \n \nActivity is quantified by release of free fluorescent 7-amino-4-methylcoumarin (AMC) which excites at 360-380 nm and emits at 440-460 nm., Echelon
- Molekulargewicht:
- 665.27
- Sequenz:
- Ac-Tyr-Val-Ala-Asp-AMC \n
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Echelon Biosciences
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
- Datenblatt des Herstellers:https://www.echelon-inc.com/product/ac-tyr-val-ala-asp-amc-caspase-1-ice-substrate-fluorogenic/
