Ac-Val-Ala-Asp-pNA (Caspase 1 (ICE) Substrate, colorimetric)
Produktgrößen
5 mg
£304,00
ECH-860-11-5MG
25 mg
£598,00
ECH-860-11-25MG
Über dieses Produkt
- SKU:
- ECH-860-11
- CAS Number:
- 149231-66-3
- Weitere Details:
- CAS Number: 149231-66-3 \nMolecular Weight: 465.18 \nSalt Form: TFA \nPurity: >96% \nSequence (3-letter): Ac-Val-Ala-Asp-pNA \nSequence (1-letter): Ac-VAD-pNA \nStorage: -20 ?C or below \n \nAc-Val-Ala-Asp-pNA is a colorimetric substrate for Caspase 1. Caspase 1/Interleukin 1b converting enzyme (ICE) is a cysteine protease that cleaves specifically at aspartic acid. ICE converts inactive IL-1 beta precursor to a pro-inflammatory cytokine that mediates a wide range of immune and inflammatory response. ICE-related cysteine proteases are required for E1A-induced, p53-dependent apoptosis in baby rat kidney (BRK) cells. Adenovirus E1B 19K protein, which is a potent inhibitor of apoptosis, inhibits activation of these proteases in BRK cells. \n \nActivity is quantified by the release of p-nitroaniline which is measured by absorbance at 405 nm., Echelon
- Molekulargewicht:
- 465.18
- Sequenz:
- Ac-Val-Ala-Asp-pNA \n
- Versandbedingungen:
- Ambient
- Lagerbedingungen:
- -20[o]C
- Hersteller:
- Echelon Biosciences
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules: Peptides
- Datenblatt des Herstellers:https://www.echelon-inc.com/product/ac-val-ala-asp-pna-caspase-1-ice-substrate-colorimetric/
