Recombinant Human IL-1B
Produktgrößen
50ug
£391,00
Y04921H-50UG
1mg
£2693,00
Y04921H-1MG
Über dieses Produkt
- SKU:
- Y04921H
- Anwendung:
- Bioactivity
- Weitere Details:
- IL-1β (Interleukin-1β) is a key pro-inflammatory cytokine that plays a central role in immune regulation, inflammatory responses, and cellular signaling. The mature form of IL-1β adopts a β-trefoil structure composed of 12 β-strands and interacts via surface residues with the IL-1R1 receptor to initiate downstream signaling. IL-1β stimulates the secretion of other inflammatory factors, such as TNF-α and IL-6, as well as chemokines, thereby mimicking an in vivo inflammatory environment. Additionally, it activates immune cells by promoting T cell proliferation, B cell differentiation, and enhancing the antigen-presenting capacity of macrophages and dendritic cells.
- Format:
- Lyophilized powder
- Formulierung:
- Lyophilized from a 0.22 um filtered solution containing 10mM PB, 5% Trehalose and 0.01% Tween 80, pH7.4
- Host:
- E. coli
- Molekulargewicht:
- 17.4 kDa
- Reinheit:
- ≥95% by SDS-PAGE
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 36 months at-20°C to-80°C in lyophilized state; 6 months at-20°C to-80°C under sterile conditions after reconstitution; 7-10 days at 2°C to 8°C under sterile conditions after reconstitution; Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- Hersteller:
- East-Mab Biomedical
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
