Recombinant Human TGF-β1
Produktgrößen
50ug
£466,00
Y04201N-50UG
1mg
£2693,00
Y04201N-1MG
Über dieses Produkt
- SKU:
- Y04201N
- Anwendung:
- Bioactivity
- Weitere Details:
- TGF-β1 (Transforming Growth Factor-β1) is a multifunctional cytokine belonging to the TGF-β superfamily. It inhibits the growth of most epithelial, endothelial, and hematopoietic cells by inducing cell cycle arrest in the G1 phase. In stem cell culture, TGF-β1 can direct the differentiation of mesenchymal stem cells into osteoblasts, chondrocytes, or adipocytes. In organoid culture systems, it regulates extracellular matrix (ECM) formation and influences tissue organization. Additionally, TGF-β1 exhibits immunomodulatory effects by suppressing the activation of T cells, B cells, NK cells, and macrophages, thereby reducing inflammatory responses. In co-culture systems—such as those involving immune and tumor cells—TGF-β1 can help mimic an immune-suppressive microenvironment.
- Format:
- Lyophilized powder
- Formulierung:
- Lyophilized from a 0.22 um filtered solution containing 0.085% TFA, 30% ACN, 5% mannitol, pH 2.5
- Host:
- Hamster
- Molekulargewicht:
- 12.8 kDa
- Reinheit:
- ≥95% by SDS-PAGE
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 36 months at-20°C to-80°C in lyophilized state; 6 months at-20°C to-80°C under sterile conditions after reconstitution; 7-10 days at 2°C to 8°C under sterile conditions after reconstitution; Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- Hersteller:
- East-Mab Biomedical
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins
