Recombinant Human HGF
Produktgrößen
50ug
£350,00
Y01701-50UG
1mg
£2177,00
Y01701-1MG
Über dieses Produkt
- SKU:
- Y01701
- Anwendung:
- Bioactivity
- Weitere Details:
- Hepatocyte Growth Factor (HGF), also known as Scatter Factor (SF), is a multifunctional cytokine primarily secreted by mesenchymal cells. It regulates diverse cellular biological behaviors by binding to its receptor c-Met, a tyrosine kinase receptor. In cell culture, HGF activates the PI3K/Akt and MAPK/ERK signaling pathways, thereby inhibiting apoptosis and promoting cell proliferation, survival, migration, and invasion. In hepatocyte culture, HGF enhances the functional maturation of liver-like cells. In organoid culture systems, it facilitates the formation of 3D structures (such as biliary networks and renal tubule branching) and regulates cell differentiation and morphogenesis.
- Format:
- Lyophilized powder
- Formulierung:
- Lyophilized from a 0.22 um filtered solution containing PBS, 5% mannitol and 0.01% Tween 80, pH 7.4
- Host:
- Hamster
- Molekulargewicht:
- 53.7 kDa (α chain), 26 kDa (β chain)
- Reinheit:
- ≥95% by SDS-PAGE
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- 36 months at-20°C to-80°C in lyophilized state; 6 months at-20°C to-80°C under sterile conditions after reconstitution; 7-10 days at 2°C to 8°C under sterile conditions after reconstitution; Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- Hersteller:
- East-Mab Biomedical
- Typ:
- Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins