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Proteine und Peptide

Recombinant Human BMP-2

Produktgrößen
50ug
£331,00
Y00421H-50UG
1mg
£1938,00
Y00421H-1MG
Über dieses Produkt
SKU:
Y00421H
Anwendung:
Bioactivity
Weitere Details:
BMP-2 (Bone Morphogenetic Protein 2), a member of the transforming growth factor-beta (TGF-β) superfamily, is synthesized in vivo as a precursor protein. Through proteolytic cleavage that removes the signal peptide and propeptide, it yields a mature peptide consisting of 114 amino acid residues. This mature peptide further forms homodimers or heterodimers via dimerization, thereby acquiring full biological activity. BMP-2 stimulates DNA synthesis and cell replication, promoting the directed differentiation of mesenchymal cells into osteoblasts. As a key factor inducing bone and cartilage formation in vivo, BMP-2 is expressed during limb growth, endochondral ossification, early fracture healing, and cartilage repair, playing a critical role in embryonic skeletal development and regenerative repair.
Format:
Lyophilized powder
Formulierung:
Lyophilized from a 0.22 um filtered solution containing 0.1M Acetic acid, 5% Trehalose, pH 3.0
Host:
E. coli
Molekulargewicht:
12.9 kDa
Reinheit:
≥95% by SDS-PAGE
Versandbedingungen:
Blue Ice
Lagerbedingungen:
36 months at-20°C to-80°C in lyophilized state; 6 months at-20°C to-80°C under sterile conditions after reconstitution; 7-10 days at 2°C to 8°C under sterile conditions after reconstitution; Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Hersteller:
East-Mab Biomedical
Typ:
Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins