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Proteine und Peptide

GMP Recombinant Human M-CSF

Produktgrößen
50ug
£651,00
G029-50UG
200ug
£4945,00
G029-200UG
Über dieses Produkt
SKU:
G029
Anwendung:
Bioactivity
Weitere Details:
M-CSF (Macrophage Colony-Stimulating Factor) is an important glycoprotein cytokine that exists as a disulfide-linked homodimer. It plays a key role in regulating the proliferation, differentiation, and survival of the monocyte-macrophage lineage. M-CSF promotes the proliferation of monocytes/macrophages, supports the differentiation of hematopoietic stem cells into monocytes and their subsequent development into macrophages, and enhances macrophage survival through anti-apoptotic signaling (e.g., upregulation of Bcl-2). Additionally, it modulates functional polarization and influences macrophage phenotype.
Format:
Lyophilized powder
Formulierung:
Lyophilized from a 0.22 um filtered solution containing 10mM PB, 5% Trehalose and 0.01% Tween 80, pH7.4
Host:
E. coli
Molekulargewicht:
18.4 kDa
Reinheit:
≥95% by SDS-PAGE
Versandbedingungen:
Blue Ice
Lagerbedingungen:
36 months at-20°C to-80°C in lyophilized state; 6 months at-20°C to-80°C under sterile conditions after reconstitution; 7-10 days at 2°C to 8°C under sterile conditions after reconstitution; Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Hersteller:
East-Mab Biomedical
Typ:
Proteins, Peptides, Small Molecules & Other Biomolecules:Recombinant Proteins