MSC-P5 Cells - Mouse cell lines
Produktgrößen
1 each
£1065,00
400294-1EACH
Über dieses Produkt
- SKU:
- 400294
- Zusätzliche Namen:
- MSCP 5, MSCP-5, MSCP5
- CE/IVD:
- RUO
- Weitere Details:
- The MSCP5 cell line, derived from murine skin keratinocytes, represents a vital tool for research in dermatology and cellular biology. This line is characterized by its robust expression of prostaglandin-H synthase 2 (PGHS-2), also known as cyclooxygenase-2 (COX-2), an enzyme critical in the prostaglandin biosynthesis pathway, which plays a pivotal role in inflammation and wound healing processes. Notably, MSCP5 cells exhibit a pronounced induction of PGHS-2 expression upon stimulation with phorbol 12-myristate 13-acetate (PMA), mimicking the cellular response to inflammatory conditions and hyperproliferative states of the epidermis. This cell line offers a unique model for investigating the regulation of COX-2 expression and its implications in skin pathophysiology, including inflammation and carcinogenesis. The PMA-induced upregulation of PGHS-2 in MSCP5 cells provides a valuable system for studying the molecular mechanisms of keratinocyte response to inflammatory stimuli, the role of prostaglandins in skin diseases, and the potential therapeutic targeting of COX-2 in dermatological conditions.
- Versandbedingungen:
- Dry Ice
- Lagerbedingungen:
- Liquid N2, -70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Cytion
- Typ:
- Cells: Cell Lines
- Datenblatt des Herstellers:2558471000724338b07c81883cce3e26