HEK293-CXCR7 Cells - Transformed cell lines
Produktgrößen
1 each
£6257,00
305421-1EACH
Über dieses Produkt
- SKU:
- 305421
- CE/IVD:
- Our cells are provided for in vitro laboratory research purposes exclusively and are not intended fo
- Weitere Details:
- Disclaimer: The prices displayed for cell lines are exclusively for not-for-profit customers. If you represent a commercial entity, please contact us for alternative pricing.The HEK293-CXCR7 cell line is a stable recombinant HEK293 cell line engineered to express the CXCR7 receptor at a low level. This cell line was developed using inscreenex's landing pad technology, ensuring precise and reproducible integration of the CXCR7 gene at a specific, pre-validated genomic locus. CXCR7, also known as ACKR3, is an atypical chemokine receptor that modulates immune responses and tumor biology. Unlike classical GPCRs, CXCR7 does not signal through G proteins; instead, it scavenges chemokines like CXCL12 and CXCL11 and forms heterodimers with CXCR4, contributing to tumor growth, metastasis, and poor prognosis in various cancers, including breast, lung, and prostate cancers. The expression of CXCR7 in this cell line was confirmed using flow cytometry with a target-specific antibody, ensuring reliable expression across the cell population. However, the receptor density was not quantified in this cell line.
- Versandbedingungen:
- Dry Ice
- Lagerbedingungen:
- Liquid N2, -70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Cytion
- Typ:
- Cells: Cell Lines
- Datenblatt des Herstellers:01917e78254670968fcb2e93b7a5fec7