NCI-H23 Cells - NCI cell lines | Lung cancer cell lines
Produktgrößen
1 each
£607,00
305044-1EACH
Über dieses Produkt
- SKU:
- 305044
- Zusätzliche Namen:
- NCI-H23, NCI.H23, NCI H23 , H-23, NCIH23
- CE/IVD:
- Our cells are provided for in vitro laboratory research purposes exclusively and are not intended fo
- Weitere Details:
- This line was established from lung cancer tissue obtained from a 59-year-old black male lung adenocarcinoma patient prior to therapy. The cells carry the mutation of K-ras 12 and a mutation in the codon 246 (ATC to ATG, isoleucine -> methionine) of the p53 gene. The cells express C-myc, L-myc, v-src, v-abl, v-erb B, c-raf 1, Ha-ras, Ki-ras and N-ras RNAs. The cell line has a heterogeneous mRNA expression for PDGF A and B chain, transforming growth factor alpha and beta and the epidermal growth factor receptor (EGFR). NCI-H23 exhibits a 20-fold higher level of c-myc DNA amplification without detectable c-myc RNA amplification. The cells stain positive for keratins 5+8 and 18 and vimentin but negative for neurofilament. The cells are L-dopa decarboxylase-negative. The cells can form colonies in soft agarose with an efficiency of 9.7%.
- Versandbedingungen:
- Dry Ice
- Lagerbedingungen:
- Liquid N2, -70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Cytion
- Typ:
- Cells: Cell Lines
- Datenblatt des Herstellers:3ecf603f51dc4845b0c228f36bab0503