IGR-1 Cells - Skin cancer cell lines
Produktgrößen
1 each
£607,00
300219-1EACH
Über dieses Produkt
- SKU:
- 300219
- Zusätzliche Namen:
- IGR 1, IGR1, Institut Gustave Roussy-1
- CE/IVD:
- Our cells are provided for in vitro laboratory research purposes exclusively and are not intended fo
- Weitere Details:
- The IGR-1 cell line is derived from a human malignant melanoma, making it a valuable model for studying the pathophysiology of melanoma and testing anti-cancer therapies. These cells are epithelial in nature and exhibit characteristics typical of aggressive melanoma, including rapid proliferation and the ability to form colonies in soft agar, a hallmark of oncogenic transformation. The IGR-1 cell line is particularly useful in research focused on understanding the molecular mechanisms driving melanoma progression, as well as in the development and testing of targeted therapies and immunotherapies. IGR-1 cells harbor mutations common in melanoma, including alterations in the MAPK/ERK pathway, which is often dysregulated in this cancer type. These mutations contribute to the cell line's ability to proliferate uncontrollably and resist apoptosis. Researchers utilize IGR-1 cells to investigate the effects of various inhibitors on this signaling pathway, providing insights into potential therapeutic strategies. Additionally, the cell line's expression of melanoma-associated antigens makes it suitable for studying immune responses against melanoma, including the development of novel immunotherapeutic approaches.
- Versandbedingungen:
- Dry Ice
- Lagerbedingungen:
- Liquid N2, -70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Cytion
- Typ:
- Cells: Cell Lines
- Datenblatt des Herstellers:1db46e2b5fd5401aa2a917bb0fd63c2b