HEL-299 Cells - Lung cancer cell lines
Produktgrößen
1 each
£607,00
300193-1EACH
Über dieses Produkt
- SKU:
- 300193
- Zusätzliche Namen:
- HEL 299, Hel-299, Hel 299, HEL299
- CE/IVD:
- Our cells are provided for in vitro laboratory research purposes exclusively and are not intended fo
- Weitere Details:
- HEL-299 is a human lung fibroblast cell line derived from an adult individual. This cell line is particularly noted for its finite capacity to propagate in culture, typically entering senescence after approximately ten passages. This characteristic makes HEL-299 a useful model for studying cellular aging and senescence, as well as the dynamics of cell growth and replication under controlled conditions. In addition to its applications in aging research, HEL-299 also serves as a model for studying signal transduction pathways. Specifically, it has been observed that the expression of the M2 muscarinic receptor in these cells is downregulated following stimulation with protein kinase C. This response highlights the cell line's utility in pharmacological research and in the investigation of mechanisms underlying receptor-mediated signaling and regulation. The alteration in receptor expression following kinase activity can provide insights into cellular responses to external stimuli, potentially aiding in the development of therapeutic strategies targeting similar pathways in various diseases.
- Versandbedingungen:
- Dry Ice
- Lagerbedingungen:
- Liquid N2, -70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Cytion
- Typ:
- Cells: Cell Lines
- Datenblatt des Herstellers:73653fa50b3944c1a93d4813c695c144