Capan-1 Cells - Pancreas cancer cell lines
Produktgrößen
1 each
£607,00
300143-1EACH
Über dieses Produkt
- SKU:
- 300143
- Zusätzliche Namen:
- CaPan-1, CAPAN-1, Capan 1, CAPAN 1, Capan1, CAPAN1
- CE/IVD:
- Our cells are provided for in vitro laboratory research purposes exclusively and are not intended fo
- Weitere Details:
- The Capan-1 cell line is derived from a human pancreatic adenocarcinoma and was established from the ascitic fluid of a 40-year-old Caucasian male. It was first characterized in 1975 and is particularly noted for its ductal epithelial morphology, which closely resembles that of primary pancreatic tumors. Capan-1 cells are extensively used in research aimed at understanding pancreatic cancer biology, including studies on tumor progression, metastasis, and treatment resistance. This cell line is well-regarded for its ability to produce mucin, a characteristic feature of many pancreatic adenocarcinomas, thus serving as a model for mucinous pancreatic cancer. Genetically, Capan-1 harbors mutations in the KRAS gene, which are typical of pancreatic cancer, as well as alterations in other cancer-related genes such as TP53 and SMAD4. These mutations make the Capan-1 cell line a valuable tool for studying the molecular mechanisms underlying pancreatic cancer and for the preclinical evaluation of new therapeutic agents targeting these pathways. Furthermore, Capan-1 cells are used to study the biology of pancreatic cancer stem cells, offering insights into the behaviors that drive cancer recurrence and resistance to conventional therapies.
- Versandbedingungen:
- Dry Ice
- Lagerbedingungen:
- Liquid N2, -70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Cytion
- Typ:
- Cells: Cell Lines
- Datenblatt des Herstellers:8f5fb9091ac84b71bcec747411635bbe