NPC1L1 Recombinant Monoclonal Antibody
Produktgrößen
50 ul
£235,00
CSB-RA921474A0HU-50UL
100 ul
£392,00
CSB-RA921474A0HU-100UL
Über dieses Produkt
- SKU:
- CSB-RA921474A0HU
- Zusätzliche Namen:
- NPC1-like intracellular cholesterol transporter 1 (Niemann-Pick C1-like protein 1), NPC1L1
- Anwendung:
- ELISA, Immunohistochemistry
- Buffer:
- phosphate buffered saline, 150mm nacl
- translate.label.attr.clone:
- 4B10
- Klonalität:
- Recombinant Monoclonal
- Weitere Details:
- Plays a major role in cholesterol homeostasis. Is critical for the uptake of cholesterol across the plasma membrane of the intestinal enterocyte. Is the direct molecular target of ezetimibe, a drug that inhibits cholesterol absorption. Lack of activity leads to multiple lipid transport defects. The protein may have a function in the transport of multiple lipids and their homeostasis, and may play a critical role in regulating lipid metabolism. Acts as a negative regulator of NPC2 and down-regulates its expression and secretion by inhibiting its maturation and accelerating its degradation.
- Immunogen:
- A synthesized peptide derived from human NPC1L1
- Isotyp:
- IgG
- Physischer Zustand:
- Liquid
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Cusabio
- Typ:
- Antibody: Recombinant Antibodies
- Datenblatt des Herstellers:NPC1L1-Antibody-12929027.html
