ADAM17 Recombinant Monoclonal Antibody
Produktgrößen
50 ul
£235,00
CSB-RA797631A0HU-50UL
100 ul
£392,00
CSB-RA797631A0HU-100UL
Über dieses Produkt
- SKU:
- CSB-RA797631A0HU
- Zusätzliche Namen:
- Disintegrin and metalloproteinase domain-containing protein 17 (ADAM 17) (EC 3.4.24.86) (Snake venom-like protease) (TNF-alpha convertase) (TNF-alpha-converting enzyme) (CD antigen CD156b), ADAM17, CSVP TACE
- Anwendung:
- ELISA, Immunofluorescence
- Buffer:
- phosphate buffered saline, 150mm nacl
- translate.label.attr.clone:
- 5A1
- Klonalität:
- Recombinant Monoclonal
- Weitere Details:
- Cleaves the membrane-bound precursor of TNF-alpha to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface. Responsible for the proteolytic release of several other cell-surface proteins, including p75 TNF-receptor, interleukin 1 receptor type II, p55 TNF-receptor, transforming growth factor-alpha, L-selectin, growth hormone receptor, MUC1 and the amyloid precursor protein. Acts as an activator of Notch pathway by mediating cleavage of Notch, generating the membrane-associated intermediate fragment called Notch extracellular truncation (NEXT). Plays a role in the proteolytic processing of ACE2.
- Immunogen:
- A synthesized peptide derived from human ADAM17
- Isotyp:
- IgG
- Physischer Zustand:
- Liquid
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Cusabio
- Typ:
- Antibody: Recombinant Antibodies
- Datenblatt des Herstellers:ADAM17-Antibody-12928874.html
