LGR5 Recombinant Monoclonal Antibody
Produktgrößen
50 ul
£235,00
CSB-RA262034A0HU-50UL
100 ul
£392,00
CSB-RA262034A0HU-100UL
Über dieses Produkt
- SKU:
- CSB-RA262034A0HU
- Zusätzliche Namen:
- Leucine-rich repeat-containing G-protein coupled receptor 5 (G-protein coupled receptor 49) (G-protein coupled receptor 67) (G-protein coupled receptor HG38), LGR5, GPR49 GPR67
- Anwendung:
- ELISA, Flow Cytometry, Western Blot
- Buffer:
- phosphate buffered saline, 150mm nacl
- translate.label.attr.clone:
- 4H8
- Klonalität:
- Recombinant Monoclonal
- Weitere Details:
- Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a stem cell marker of the intestinal epithelium and the hair follicle. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. Involved in the development and/or maintenance of the adult intestinal stem cells during postembryonic development.
- Immunogen:
- A synthesized peptide derived from human LGR5/GPR49
- Isotyp:
- IgG
- Physischer Zustand:
- Liquid
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Rat
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Cusabio
- Typ:
- Antibody: Recombinant Antibodies
- Datenblatt des Herstellers:LGR5-Antibody-12928713.html
