MEN1 Recombinant Monoclonal Antibody
Produktgrößen
50 ul
£235,00
CSB-RA242999A0HU-50UL
100 ul
£392,00
CSB-RA242999A0HU-100UL
Über dieses Produkt
- SKU:
- CSB-RA242999A0HU
- Zusätzliche Namen:
- Menin, MEN1, SCG2
- Anwendung:
- ELISA, Western Blot
- Buffer:
- phosphate buffered saline, 150mm nacl
- translate.label.attr.clone:
- 8G11
- Klonalität:
- Recombinant Monoclonal
- Weitere Details:
- Essential component of a MLL/SET1 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3 (H3K4). Functions as a transcriptional regulator. Binds to the TERT promoter and represses telomerase expression. Plays a role in TGFB1-mediated inhibition of cell-proliferation, possibly regulating SMAD3 transcriptional activity. Represses JUND-mediated transcriptional activation on AP1 sites, as well as that mediated by NFKB subunit RELA. Positively regulates HOXC8 and HOXC6 gene expression. May be involved in normal hematopoiesis through the activation of HOXA9 expression (By similarity). May be involved in DNA repair.
- Immunogen:
- A synthesized peptide derived from human Menin
- Isotyp:
- IgG
- Physischer Zustand:
- Liquid
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Cusabio
- Typ:
- Antibody: Recombinant Antibodies
- Datenblatt des Herstellers:MEN1-Antibody-12928824.html
