IFNAR1 Recombinant Monoclonal Antibody
Produktgrößen
50 ul
£235,00
CSB-RA011046A0HU-50UL
100 ul
£392,00
CSB-RA011046A0HU-100UL
Über dieses Produkt
- SKU:
- CSB-RA011046A0HU
- Zusätzliche Namen:
- Interferon alpha/beta receptor 1, IFN-R-1, IFN-alpha/beta receptor 1, Cytokine receptor class-II member 1, Cytokine receptor family 2 member 1, CRF2-1, Type I interferon receptor 1, IFNAR1, IFNAR
- Anwendung:
- ELISA
- Buffer:
- phosphate buffered saline
- translate.label.attr.clone:
- 1B12
- Klonalität:
- Recombinant Monoclonal
- Weitere Details:
- Component of the receptor for type I interferons, including interferons alpha, IFNB1 and IFNW1 (PubMed:2153461, PubMed:7665574, PubMed:10049744, PubMed:14532120, PubMed:15337770, PubMed:21854986). Functions in general as heterodimer with IFNAR2 (PubMed:7665574, PubMed:10049744, PubMed:21854986). Type I interferon binding activates the JAK-STAT signaling cascade, and triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and the IFNR alpha- and beta-subunits themselves (PubMed:7665574, PubMed:21854986). Can form an active IFNB1 receptor by itself and activate a signaling cascade that does not involve activation of the JAK-STAT pathway (By similarity).
- Immunogen:
- A synthesized peptide derived from human IFNAR1
- Isotyp:
- IgG
- Physischer Zustand:
- Liquid
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Cusabio
- Typ:
- Antibody: Recombinant Antibodies
- Datenblatt des Herstellers:IFNAR1-Antibody-12923433.html