GRIA2/GRIA3 Recombinant Monoclonal Antibody
Produktgrößen
50 ul
£235,00
CSB-RA009900A0HU-50UL
100 ul
£392,00
CSB-RA009900A0HU-100UL
Über dieses Produkt
- SKU:
- CSB-RA009900A0HU
- Zusätzliche Namen:
- Glutamate receptor 2, GluR-2, AMPA-selective glutamate receptor 2, GluR-B, GluR-K2, Glutamate receptor ionotropic, AMPA 2, GluA2, GRIA2, GLUR2, Glutamate receptor 3, GluR-3, AMPA-selective glutamate receptor 3, GluR-C, GluR-K3, Glutamate receptor ionotropic, AMPA 3, GluA3, GRIA3, GLUR3, GLURC
- Anwendung:
- ELISA, Immunofluorescence
- Buffer:
- phosphate buffered saline
- translate.label.attr.clone:
- 4C3
- Klonalität:
- Recombinant Monoclonal
- Weitere Details:
- Receptor for glutamate that functions as ligand-gated ion channel in the central nervous system and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate. Through complex formation with NSG1, GRIP1 and STX12 controls the intracellular fate of AMPAR and the endosomal sorting of the GRIA2 subunit toward recycling and membrane targeting (By similarity).
- Immunogen:
- A synthesized peptide derived from human GRIA2/GRIA3
- Isotyp:
- IgG
- Physischer Zustand:
- Liquid
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Cusabio
- Typ:
- Antibody: Recombinant Antibodies
- Datenblatt des Herstellers:GRIA2GRIA3-Antibody-12923418.html
