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Antikörper

KDM4B Antibody

Produktgrößen
50 ul
£186,00
CSB-PA991708-50UL
100 ul
£334,00
CSB-PA991708-100UL
Über dieses Produkt
SKU:
CSB-PA991708
Zusätzliche Namen:
JHDM3B antibody; JmjC domain-containing histone demethylation protein 3B antibody; JMJD2B antibody; Jumonji domain containing 2B antibody; Jumonji domain containing protein 2B antibody; Jumonji domain-containing protein 2B antibody; Kdm4b antibody; KDM4B_HUMAN antibody; KIAA0876 antibody; Lysine (K) specific demethylase 4B antibody; Lysine demethylase 4B antibody; Lysine-specific demethylase 4B antibody; TDRD14B antibody; Tudor domain containing 14B antibody
Anwendung:
ELISA, Immunohistochemistry
Buffer:
PBS
Klonalität:
Polyclonal
Weitere Details:
JMJD2B (JmjC domain-containing histone demethylation protein 3A) is a 1,064 amino acid protein encoded by the human gene JMJD2B. JMJD2B belongs to the JMJD2B histone demethylase family and contains one JmjC domain, one JmjN domain, two PHD-type zinc fingers and two Tudor domains. The two Tudor domains recognize and bind methylated histones and have an interdigitated structure; the unusual fold is required for its ability to bind methylated histone tails. JMJD2B is a histone demethylase that specifically demethylates Lys 9 residues of Histone H3, thereby playing a role in histone code. It does not demethylate Histone H3 Lys 4, H3 Lys 27, H3 Lys 36 or H4 Lys 20, however, and is only able to demethylate trimethylated H3 Lys-9 and has weaker activity than JMJD2A, JMJD2C and JMJD2D. JMJD2B demethyl-ation of Lysine residues will generate formaldehyde and succinate. JMJD2B is a ubiquitously expressed nuclear protein.
Host:
Rabbit
Immunogen:
Synthetic peptide of Human KDM4B
Isotyp:
IgG
Physischer Zustand:
Liquid
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Hersteller:
Cusabio
Typ:
Antibody: Polyclonal Antibody