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Antikörper

ERAP1 Antibody

Produktgrößen
100 ul
£332,00
CSB-PA987708-100UL
Über dieses Produkt
SKU:
CSB-PA987708
Zusätzliche Namen:
A LAP antibody; A-LAP antibody; Adipocyte derived leucine aminopeptidase antibody; Adipocyte-derived leucine aminopeptidase antibody; ALAP antibody; Aminopeptidase PILS antibody; Aminopeptidase regulator of TNFR1 shedding antibody; APPILS antibody; ARTS 1 antibody; ARTS-1 antibody; Arts1 antibody; Endoplasmic reticulum aminopeptidase 1 antibody; Endoplasmic reticulum aminopeptidase associated with antigen processing antibody; ERAAP antibody; ERAAP1 antibody; ERAP 1 antibody; Erap1 antibody; ERAP1_HUMAN antibody; KIAA0525 antibody; kiaa0525 protein antibody; PILS AP antibody; PILS-AP antibody; PILSA antibody; PILSAP antibody; Puromycin insensitive leucyl specific aminopeptidase antibody; Puromycin-insensitive leucyl-specific aminopeptidase antibody; Type 1 tumor necrosis factor receptor shedding aminopeptidase regulator antibody; type 1 tumor necrosis factor receptors shedding aminopeptidase regulator antibody; VEGF-induced aminopeptidase antibody
Anwendung:
ELISA, Western Blot
Buffer:
phosphate buffered saline (without mg2+ and ca2+)
Klonalität:
Polyclonal
Weitere Details:
Aminopeptidase that plays a central role in peptide trimming, a step required for the generation of most HLA class I-binding peptides. Peptide trimming is essential to customize longer precursor peptides to fit them to the correct length required for presentation on MHC class I molecules. Strongly prefers substrates 9-16 residues long. Rapidly degrades 13-mer to a 9-mer and then stops. Preferentially hydrolyzes the residue Leu and peptides with a hydrophobic C-terminus, while it has weak activity toward peptides with charged C-terminus. May play a role in the inactivation of peptide hormones. May be involved in the regulation of blood pressure through the inactivation of angiotensin II and/or the generation of bradykinin in the kidney. Hattori A., J. Biochem. 130:235-241(2001). Nakajima D., DNA Res. 9:99-106(2002). Clark H.F., Genome Res. 13:2265-2270(2003).
Host:
Rabbit
Immunogen:
Synthesized peptide derived from internal of Human ARTS-1.
Isotyp:
IgG
Physischer Zustand:
Liquid
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human, Mouse, Rat
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Hersteller:
Cusabio
Typ:
Antibody: Polyclonal Antibody