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Antikörper

NBN (Ab-343) Antibody

Produktgrößen
100 ul
£332,00
CSB-PA985787-100UL
Über dieses Produkt
SKU:
CSB-PA985787
Zusätzliche Namen:
AT V1 antibody; AT V2 antibody; ATV antibody; Cell cycle regulatory protein p95 antibody; FLJ10155 antibody; MGC87362 antibody; Nbn antibody; NBN_HUMAN antibody; NBS 1 antibody; NBS antibody; NBS1 antibody; Nibrin antibody; Nijmegen breakage syndrome 1 (nibrin) antibody; Nijmegen breakage syndrome antibody; Nijmegen breakage syndrome protein 1 antibody; p95 antibody; p95 protein of the MRE11/RAD50 complex antibody
Anwendung:
ELISA, Immunohistochemistry, Western Blot
Buffer:
phosphate buffered saline (without mg2+ and ca2+)
Klonalität:
Polyclonal
Weitere Details:
Mutations in p95/NBS1 gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. Hsu HL, et al (2005)Oncogene; 24(31): 4956-64. Falck J, et al. (2005) Nature; 434(7033): 605-11. Buscemi G, et al. (2004) Oncogene; 23(46): 7691-700. Beausoleil SA, et al. (2004) Proc Natl Acad Sci U S A; 101(33): 12130-5.
Host:
Rabbit
Immunogen:
Peptide sequence around aa.341~345 (S-L-S-Q-G) derived from Human p95/NBS1.
Isotyp:
IgG
Physischer Zustand:
Liquid
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Hersteller:
Cusabio
Typ:
Antibody: Polyclonal Antibody