PLAU Antibody
Produktgrößen
50 ul
£186,00
CSB-PA960570-50UL
100 ul
£334,00
CSB-PA960570-100UL
Über dieses Produkt
- SKU:
- CSB-PA960570
- Zusätzliche Namen:
- ATF antibody; ATF uPA antibody; BDPLT5 antibody; Plasminogen activator antibody; Plasminogen activator urinary antibody; Plasminogen activator urokinase antibody; PLAU antibody; QPD antibody; u PA antibody; U plasminogen activator antibody; u-PA antibody; U-plasminogen activator antibody; uPA antibody; URK antibody; UROK_HUMAN antibody; Urokinase plasminogen activator antibody; Urokinase type plasminogen activator antibody; Urokinase type plasminogen activator precursor antibody; Urokinase-type plasminogen activator chain B antibody
- Anwendung:
- ELISA, Immunohistochemistry
- Buffer:
- PBS
- Klonalität:
- Polyclonal
- Weitere Details:
- This gene encodes a serine protease involved in degradation of the extracellular matrix and possibly tumor cell migration and proliferation. A specific polymorphism in this gene may be associated with late-onset Alzheimer's disease and also with decreased affinity for fibrin-binding. This protein converts plasminogen to plasmin by specific cleavage of an Arg-Val bond in plasminogen. Plasmin in turn cleaves this protein at a Lys-Ile bond to form a two-chain derivative in which a single disulfide bond connects the amino-terminal A-chain to the catalytically active, carboxy-terminal B-chain. This two-chain derivative is also called HMW-uPA (high molecular weight uPA). HMW-uPA can be further processed into LMW-uPA (low molecular weight uPA) by cleavage of chain A into a short chain A (A1) and an amino-terminal fragment. LMW-uPA is proteolytically active but does not bind to the uPA receptor. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- Host:
- Rabbit
- Immunogen:
- Fusion protein of Human PLAU
- Isotyp:
- IgG
- Physischer Zustand:
- Liquid
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Cusabio
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:PLAU-Antibody-11099928.html
