BCAS3 Antibody
Produktgrößen
50 ul
£186,00
CSB-PA952743-50UL
100 ul
£334,00
CSB-PA952743-100UL
Über dieses Produkt
- SKU:
- CSB-PA952743
- Zusätzliche Namen:
- 1500019F07Rik antibody; 2610028P08Rik antibody; AU021018 antibody; BC028339 antibody; BCAS3 antibody; BCAS3_HUMAN antibody; Breast carcinoma-amplified sequence 3 antibody; FLJ20128 antibody; GAOB1 antibody; K20D4 antibody; MAAB antibody; Maab1 protein antibody; MGC4973 antibody; rudhira antibody
- Anwendung:
- ELISA, Immunohistochemistry
- Buffer:
- PBS
- Klonalität:
- Polyclonal
- Weitere Details:
- BCAS3 (breast carcinoma amplified sequence 3), also designated MAAB or GAOB1, is a 913 amino acid protein that is believed to be involved in breast cancer progression. The gene is regulated by ER (estrogen receptor alpha) and expressed in multiple tissues, including malignant human brain lesions. It is overexpressed and amplified in breast cancer cell lines. BCAS3 contains three WD40 repeat regions, a bromodomain, a rare zinc-finger motif, four probable DNA-binding domains, and two kinase-inducible phosphorylation domains. Five variants are produced due to alternative splicing. BCAS3 interacts with histone H3 and PCAF, which is indicative of histone acetyltransferase activity. BCAS3 also exhibits ER transactiviation activity by acting as a coactivator with PELP1 or MTA1. The amplification and translocation between the BCAS3 gene and the BCAS4 gene results in a fusion transcript is overexpressed in MCF-7 cells.
- Host:
- Rabbit
- Immunogen:
- Synthetic peptide of Human BCAS3
- Isotyp:
- IgG
- Physischer Zustand:
- Liquid
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Cusabio
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:BCAS3-Antibody-11103717.html
