E2F6 Antibody
Produktgrößen
100 ul
£332,00
CSB-PA945555-100UL
Über dieses Produkt
- SKU:
- CSB-PA945555
- Zusätzliche Namen:
- E2F 6 antibody; E2F binding site modulating activity protein antibody; E2F transcription factor 6 antibody; E2F transcription factor 6 isoform 1 antibody; E2F-6 antibody; E2F6 antibody; E2F6_HUMAN antibody; EMA antibody; MGC111545 antibody; Transcription factor E2F6 antibody
- Anwendung:
- ELISA, Immunohistochemistry, Western Blot
- Buffer:
- phosphate buffered saline (without mg2+ and ca2+)
- Klonalität:
- Polyclonal
- Weitere Details:
- Inhibitor of E2F-dependent transcription. Binds DNA cooperatively with DP proteins through the E2 recognition site, 5'-TTTC[CG]CGC-3'. Has a preference for the 5'-TTTCCCGC-3' E2F recognition site. E2F6 lacks the transcriptional activation and pocket protein binding domains. Appears to regulate a subset of E2F-dependent genes whose products are required for entry into the cell cycle but not for normal cell cycle progression. May silence expression via the recruitment of a chromatin remodeling complex containing histone H3-K9 methyltransferase activity. Overexpression delays the exit of cells from the S-phase. Matthew J. Oberley, J. Biol. Chem., Oct 2003; 278: 42466 - 42476. Claire Attwooll, J. Biol. Chem., Jan 2005; 280: 1199 - 1208. Paloma H. Giangrande, Genes & Dev., Dec 2004; 18: 2941 - 2951. J?rg Storre, J. Biol. Chem., Dec 2005; 280: 41380 - 41386.
- Host:
- Rabbit
- Immunogen:
- Synthesized peptide derived from Human E2F6.
- Isotyp:
- IgG
- Physischer Zustand:
- Liquid
- Aufreinigung:
- Affinity Purified
- Reaktivitäten:
- Human, Mouse
- Versandbedingungen:
- Blue Ice
- Lagerbedingungen:
- -20[o]C/-70[o]C Avoid freeze/thaw cycles.
- Hersteller:
- Cusabio
- Typ:
- Antibody: Polyclonal Antibody
- Datenblatt des Herstellers:E2F6-Antibody-11084536.html
