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Antikörper

PTK2 (Ab-861) Antibody

Produktgrößen
100 ul
£332,00
CSB-PA939147-100UL
Über dieses Produkt
SKU:
CSB-PA939147
Zusätzliche Namen:
FADK 1 antibody; FADK antibody; FAK related non kinase polypeptide antibody; FAK1 antibody; FAK1_HUMAN antibody; Focal adhesion kinase 1 antibody; Focal adhesion Kinase antibody; Focal adhesion kinase isoform FAK Del33 antibody; Focal adhesion kinase related nonkinase antibody; FRNK antibody; p125FAK antibody; pp125FAK antibody; PPP1R71 antibody; Protein phosphatase 1 regulatory subunit 71 antibody; Protein tyrosine kinase 2 antibody; Protein-tyrosine kinase 2 antibody; Ptk2 antibody; PTK2 protein tyrosine kinase 2 antibody
Anwendung:
ELISA, Immunohistochemistry, Western Blot
Buffer:
phosphate buffered saline (without mg2+ and ca2+)
Klonalität:
Polyclonal
Weitere Details:
Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Plays a potential role in oncogenic transformations resulting in increased kinase activity. Shi Q, et al. (2003) Mol Biol Cell; 14(10): 4306-15. Vadlamudi RK, et al. (2003) FEBS Lett; 543(1-3): 76-80. Eliceiri BP, et al. (2002) J Cell Biol Apr 01; 157(1): 149-60. Abu-Ghazaleh R, (2001) et al. Biochem J; 360(Pt 1): 255-64. Slack JK, et al.(2001) Oncogene; 20(10): 1152-63.
Host:
Rabbit
Immunogen:
Peptide sequence around aa. 859~863 (H-I-Y-Q-P) derived from Human FAK.
Isotyp:
IgG
Physischer Zustand:
Liquid
Aufreinigung:
Affinity Purified
Reaktivitäten:
Human, Mouse, Rat
Versandbedingungen:
Blue Ice
Lagerbedingungen:
-20[o]C/-70[o]C Avoid freeze/thaw cycles.
Hersteller:
Cusabio
Typ:
Antibody: Polyclonal Antibody